Clinical features and outcomes of focal segmental glomerulosclerosis pathologic variants in Korean adult patients
نویسندگان
چکیده
منابع مشابه
Clinical features and outcomes of focal segmental glomerulosclerosis pathologic variants in Korean adult patients
BACKGROUND Many studies have shown that clinical characteristics and outcomes differ depending on pathologic variants of focal segmental glomerulosclerosis (FSGS). However, these are not well defined in Asian populations. METHODS This retrospective study evaluated clinical features and outcomes of pathologic FSGS variants in 111 adult patients between January 2004 and December 2012. Primary o...
متن کاملPathologic classification of focal segmental glomerulosclerosis.
Focal segmental glomerulosclerosis (FSGS) is defined as a clinical-pathologic syndrome manifesting proteinuria and focal and segmental glomerular sclerosis with foot process effacement. The pathologic approach to the classification of FSGS is complicated by the existence of primary (idiopathic) forms and multiple subcategories with etiologic associations, including human immunodeficiency virus ...
متن کاملPresenting features and short-term outcome according to pathologic variant in childhood primary focal segmental glomerulosclerosis.
BACKGROUND This was a retrospective analysis of children in one center who had primary (idiopathic) FSGS. DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS There were 41 patients: 34.1% female, 65.9% male, 80.5% black, and 19.5% white. At presentation, the mean age was 10.9 +/- 0.9 yr. The mean time of follow-up was 3.9 +/- 0.5 yr. RESULTS During the observation period, the systolic BP (SBP) ...
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INTRODUCTION The clinical significance of histologic variants of primary focal segmental glomerulosclerosis (FSGS) remains unclear. With the aim to determine presentation and outcome of the variants of FSGS in a hispanic population, we studied our cases of this glomerulopathy. METHODS In this retrospective study, all renal biopsies with FSGS (1998-2009), were classified according to the Colum...
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Treatment of nephrotic syndrome due to minimal change disease and focal segmental glomerulosclerosis remains a challenge since steroid dependence, steroid resistance and a relapsing disease course exhibits a high cumulative steroid dosage. The necessity of using alternative steroid-sparing immunosuppressive agents with potential toxic side effects also restricts their long-term use. Rituximab, ...
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ژورنال
عنوان ژورنال: BMC Nephrology
سال: 2014
ISSN: 1471-2369
DOI: 10.1186/1471-2369-15-52